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The effects of these drugs on mood, daytime sleepiness, and some measures of sleep quality were assessed before and after one month of treatment.The researchers compared the effects of all drugs on daytime sleepiness and mood, noting that very few studies so far have made these comparisons.Additional administration of epinephrine, often in the form of an autoinjector (Epi-pen), is required by people with such hypersensitivities.H-antihistamines can be administered topically (through the skin, nose, or eyes) or systemically, based on the nature of the allergic condition.Once the mast cell-antibody-antigen complex is formed, a complex series of events occurs that eventually leads to cell degranulation and the release of histamine (and other chemical mediators) from the mast cell or basophil.Once released, the histamine can react with local or widespread tissues through histamine receptors.Their main benefit is they primarily affect peripheral histamine receptors and therefore are less sedating.

In severe allergies, such as anaphylaxis or angioedema, these effects may be of life-threatening severity.

Some common kinds you can buy over the counter include: Note: Some antihistamines are mixed with other medicines.

These could include pain relievers or decongestants.

Many of the brand names above are for these combination medicines.

These are meant to treat many symptoms at the same time.

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