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Growing up in an environment perceived as invalidating is one factor commonly discussed as contributing to the development of borderline personality disorder (BPD).

Coupled with a genetic tendency to be over-emotional, an invalidating environment is theorized to be one of the two major causes of BPD.

Biosocial Theory is a theory in behavioral and social science that describes personality disorders and mental illnesses and disabilities as biologically-determined personality traits reacting to environmental stimuli. The disorder is characterized by heightened sensitivity to emotion, increased emotional in-tensity [sic] and a slow return to emotional baseline.

Linehan wrote in her 1993 paper, Cognitive–Behavioral Treatment of Borderline Personality Disorderm that "the biosocial theory suggests that BPD is a disorder of self-regulation, and particularly of emotional regulation, which results from biological irregularities combined with certain dysfunctional environments, as well as from their interaction and transaction over time" According to a 1999 article published by Mc Clean Hospital "DBT is based on a biosocial theory of personality functioning in which BPD is seen as a biological disorder of emotional regulation.

Werner and Gross indicate that problems with emotional regulation account for upwards of 75% of disorders in the , making the biosocial theory widely adaptable.

Invalidators let it be known directly or indirectly that their target’s views and feelings do not count for anything to anybody at any time or in any way.Regardless of the means, the effect is clear: the person's feelings are “wrong.”An environment perceived as invalidating generally means that the child grows up feeling that his emotional responses are not correct or considered in the regular course of things.Over time, this can result in confusion and a general distrust of a person’s own emotions.The biosocial theory can be widely applied, and it is certainly widely accepted.Despite the wide applicability and acceptance of the biosocial theory, it does not capture everyone's theories of their problems and how to solve them.

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